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Farfield

英国Farfield www.farfield-sensors.com.cn  www.farfield-group.com
英国Farfield公司致力于为全球的生物学蛋白检测、表面科学及纳米科技领域提供创新的科学分析仪器,使用户在分子甚至原子的层面上理解物质之间的相互作用及作用期间的实时变化,给出相应的动力学及热力学参数,如:分子直径、厚度、密度、表面浓度及固-液、液-液界面薄膜实时反应和变化。公司核心的DPI (Dual Polarization Interferometry)技术及基于DPI技术的AnaLight系列双偏振极化干涉测量分析系统应用范围包括: 
蛋白质科学研究应用:
1、定量测量蛋白质构象变化分析
2、蛋白质聚集、折叠分析(Alzheimer's等神经退行性疾病)
3、蛋白质与小分子(如药物小分子、金属离子等)间相互作用
4、膜、脂和蛋白质间相互作用
5、蛋白质和多肽等大分子间相互作过程分析、药物筛选
6、抗原-抗体;受体-配体

表面分析应用:
1、表活剂、聚合物等界面相互作用研究
2、界面物理化学、界面科学、洗脱研究
3、胶体表面化学中两亲分子有序组合体和分子自组装研究
4、生物材料表面化学(如隐形眼镜、体内植入体等) 

  DPI为定量测量技术,尤其在蛋白质结构及蛋白质与小分子之间的相互作用的研究领域突破目前所有其它即时测量分子动力学技术的瓶颈。该技术在上述领域应用广泛并发表大量文献。被称做”分子显微镜“的DPI仪器是目前测量分子相互作用时结构及构象变化最灵敏的技术平台。由于DPI技术具有极高的灵敏度,能够测量分子之间相互作用时分子层中<0.1A厚度及<0.1pg/平方毫米密度的实时的变化(如分子量为100000Da的蛋白和分子量为50Da的小分子相互作用,感应灵敏度<5Da),并给出动力学及热力学变化曲线,因此DPI技术提供的数据与核磁共振(NMR)、X射线晶体衍射(X-ray Crystallograph)及中子反射等相比更具有优越性, 是其他生物传感技术如SPR、QCM等无法比拟的。 
Farfield Scientific Inc. leads the field as an innovator, developer and supplier of analytical instruments designed to address the emerging and evolving molecular-scale measurement demands of scientific discovery. Our tools and solutions meet and exceed the most rigorous measurement challenges faced by scientific research in the United States over the next decade.
Our instruments are advancing the frontiers of molecular research in biophysics, surface science and nanotechnology. Our customers are at the forefront of their research fields. Our products are based on a complete understanding and independent verification of the underlying physics of metrology.
Farfield Instruments provide results in "real time", providing our customers with information that can make immediate impact on their analysis, research and speed of products to market.
The support we provide to our customers, and the progress our customers make, is based on Farfield's active engagement with your scientific community. We share your molecular-scale research aspirations and succeed through your science.
Farfield Scientific Inc. is a member of the Farfield Group of Companies
Location & Contact
We would like to hear from you and to discuss ways we can engage and accelerate your research programs.
Farfield Scientific Inc. headquarters office is located in Pittsburgh, Pennsylvania
Farfield Scientific Inc.
4514 Plummer Street
Pittsburgh, PA 15201
Tel: 412 802 8669
Fax: 412 802 0779
e-mail: usa@farfield-group.com